NADplus+ complex: cell energy booster with DNA protection:
AIM AND RESULT: healthy ageing from the inside out!
NADplus + = 1st nutraceutical according to studies that is truly anti-ageing (healthy ageing)
19 active ingredients, including NAD (Nicotinamide adenine dinucleotide) = decelerating the ageing process.
- Excellent anti-oxidative characteristics
- Collagen boosting
- Improved immunity
- Improved skin hydration
- Energy boosting of human cells
- Promotion of cell longevity
- DNA protection
According to RDA of NAD + = separate buying of ingredients – R3400.00
Why do we age….? Is it impossible to evaluate one’s beauty without investing in the care of what's inside the body? How does your lifestyle affect your health? In what way does it alter your physical characteristics?
The 4 Killers
- Glycation – conscious & unconscious sugar intake.
- Oxidation – stress – high homocysteine, excess oestrogen
We are living longer, but not necessarily better lives!
Influences which genes are activated and which are not. Is the biochemical process essential to maintain the functionality of cells? Vitamins, hormones, neurotransmitters and antibodies work only if methylation occurs correctly. Another crucial role of methylation is to reduce high blood levels of homocysteine, a toxic compound produced during cell metabolism. Unfortunately, as we age, methylation becomes less effective.
The result is an increase in the opportunity for poor cellular function and disease.
We need certain vitamins and minerals to regulate methylation. If a person diet lacks these vitamins and minerals there is not enough methyl groups to make methyl happen. This leads to disease and poor health and the increase in blood levels of homocysteine.
Aside from an unhealthy diet, not getting daily exercise may also contribute to poor methylation. Faulty methylation leads to high levels of homo-cysteine. Elevated levels are a risk indicator of health issues, including cardiovascular disease.
Sustain the process of methylation through healthy eating and exercise is vital for health and longevity.
Sneak attack of sugars. When you eat sugars or refined carbohydrates, the body turns them into glucose. High levels of blood glucose in turn created sugar-coated proteins, which go onto form Advanced Glycation (AGE’s). These AGE’s leads to stiffening of protein fibres (skin, hair, nails, organs) e.g. collagen and elastin fibres, formation of wrinkles and reduced capacity of healing.
Reason why we don’t see harm when we younger, our youthful bodies have more defences to block the damage plus we still produce collagen. At 30 you have decades of harmful AGE’s UV rays and air pollution. This is the time many people start to see changes in ageing skin.
Damage from glycation isn’t limited to skin. It compromises the function of bones, tendons, cartilages, teeth, muscle and cardiovascular system. Research has also shown that chronic levels of high blood glucose could increase your chances for developing diabetes and heart disease, in other words a decrease in longevity.
Even though we can’t eliminate sugar completely in our diets – we need glucose to live. It’s an essential fuel for our cells. Making better lifestyle choices can help.
Now that researches know that glycation is a primary cause of skin ageing, anti-ageing creams and supplements are formulated that fights AGE’s and aim to stimulate the fibroblast to build new collagen.
Every minute every day the cells in our body have huge quantities of molecules called free radicals. Free radicals are unstable molecules that contain certain electrons. Electron prefer to be paired with another electron in order to have a balanced electrical charge. This is called oxidative stress. It’s a natural process like breathing. But our bodies do an excellent job of keeping free radicals in check. It happens with antioxidants we need in our diet.
Over time our body ability to control oxidative stress becomes slightly less efficient. In addition to this natural oxidative stress, our habits and activities can contribute to even more oxidative stress. Smoking, UV sunlight and environmental toxins also leads to production of free radicals in the body.
So how does it impact our health and appearance? When free radicals attack our skin, they speed up formation of wrinkles and other imperfections. But there is also damage we don’t see. Like macro and microscopic structures of the human body.
When FR cause damage to lipids of cellular membranes the f=defensive barrier is harmed. Such oxidation infuses inflammation and causes early onset ageing. FR also oxidase DNA and RNA – essentially what constitute our genetic makeup during oxidation, structural (HA and collagen) and regulatory proteins are oxidase, causing structural and functional damage to our bodies – including our skin.
Inflammation is one of the body’s most important defences against trauma and infection. Think of it as your own SUPERHERO protecting you against invading viruses and bacteria.
It comes to rescue when we fall and scrape a knee or break a leg. Without inflammation bruises and wounds wouldn’t heal. Inflammation response directs more blood flow to the area of injury; this includes white blood cells, which fight off infection. Doctors refer to this as acute inflammation.
But just like many comic book superheroes, inflammation can have a dark side. That’s when beneficial acute inflammation becomes chronic inflammation. It can fight against perfectly healthy cells and cause disease. When this happens, inflammation becomes a negative force with regard to health.
Ageing is characterised by a chronic state of slight inflammation tied to both genetics and individual development of immune system responses. In the long run, this inflammatory process may compromise organs and reduce longevity by increasing to certain risk factors.
This fact makes inflammation a silent threat that grows stronger day by day. One of the main ways to combat chronic inflammation is through healthy lifestyle habits; focus your efforts on relaxing your mind, getting regular exercise and eating foods that contain anti-inflammatory com-pounds (like veggies and nuts) and nutraceuticals. THINK of these habits as your very own team of superheroes to help to be as healthy as you can be…
This makes you think…
130 years ago, women reached age 39 on average, and men age 43.
Now – double as old – genetically 100 years of age = 75-100yr olds – not a pretty picture, we are getting older due to better hygiene, sanitation, immunisation, modern western medicine, no wars (but we aren’t ready for old age – disease ridden)
BUT limited in mobility, challenged in mental faculties, bad/sad physical appearance etc
1945: no synthetic chemicals, now there are over 100 000.
8 – 10 x more stress
We sleep on average 2 hrs a night less
Inflammation and DNA damage associated with massive amounts of toxins – human body cannot cope with – resulting in increased levels of free radicals and inflammatory damage. PLUS, modern life with multitude stressors, little sleep, less exercise and poor toxic diets = POOR AGEING instead of HEALTHY ageing.
We need a focus shift from REACTIVE to PRO-ACTIVE
Main reason for pre-mature and accelerated ageing/ degenerative disorders = DNA damage and inflammation
We are stuck in an illness model, instead of a healthy model.
Millennials are thinking pro-actively – at age 28 already thinking of old age
Life span is there… where is HEALTH SPAN?
NAD + complex = answer to healthy ageing process
Easiest way to understand what the skin needs: embryo (cluster of cells) 1st 2 layers: an outer ectoderm and an inner endoderm. The ectodermal cells forms the entire nervous system, including your brain, spinal cord and peripheral nerves, outer skin and glands, hair, nails and linings of mouth and anal canal. Endodermal cells become the outer linings of digestive tract, respiratory tract, urinary bladder and urethra. The 3rd layer forms later, called the mesoderm forms all interior tissues like muscle, bone, blood, lymph and lining of body cavities.
Very close relationship between skin and brain from the beginning – therefore feed them the same!
3 complexes: All pH encapsulated – absorbed in different parts of digestive system for optimal result.
- Anti-oxidant: Pink
Oxidation (robbing cells of electrons) = rust = inflammation (think about it: the more oxidation/rust, the quicker onset of sickness e.g. cancer, diabetes etc
Actively targeting free radicals, added protection against inflammation
Antioxidants made in body, but overload of free radicals in modern life and excessive demand on natural supply – MUST supplement
- NAD + complex: White
Co enzyme working within mitochondria (power station) by enhancing metabolism and generate energy - it is present in ALL cells
Enhances cell energy, protects DNA
Cells having more fuel via NAD have more energy, function much better, live much longer and stay healthy.
- Detox complex: Grey
Liver (specifically phase 2: environmental toxin removal) and gut – disaster area due to demand
Assist the liver’s regeneration and detoxification process, getting rid of many toxins of modern life
Both 1 and 3 will slow down degeneration and ageing by blocking inflammation caused by free radicals and toxins in body and skin cells.
Ingredients in NADplus+ Complex
NAD co enzyme 75mg:
Without NAD our bodies can’t make energy
The body defend and heal itself – depleted energy by age: DNA breakdown plus shorter strands
NAD – protect DNA and stimulate more energy within nucleus
Enhances the generation of energy in the cells at cellular level
Latest worldwide scientific studies prove that NAD+ is an essential, natural substrate for certain proteins (important enzymes that regulate over 200 biological processes in body such as stress response, cell metabolism and ageing process.
Nadplus+ prevents cell death by protecting the telomeres
DNA – Telomeres: part of DNA must be at specific length – if not (due to age/ cell death/ genetic diseases/ stress/ medication/ quality of life – premature ageing and risk of genetic diseases and cancer. Nadplus+ impacts the length of telomeres thus enhancing longevity of cells and prevents cell death.
Alpha lipoic Acid 50mg:
Universal anti ager (super/universal anti-oxidant)
Co enzyme Q10 75mg:
It makes new mitochondria (power station)
Works very closely with NAD as NAD will fuel the power station
AGEs – advanced glycation end products – end result of chemical process when structures of proteins are warped by exposure to sugars
AGE chemistry = “browning” roast chicken, toast – at work every day in body = ageing
The results of AGE: loss of function, disease, ageing, ultimately death
AGEs transform youth into old age!!
AGEs in tissues increase free radical production 50 times more than un-glycated proteins.
CO enzyme Q10 PLUS resveratrol – helps against AGE onslaught to stop AGE formation
Mimics longevity effect of calorie-restricted diet
Red wine compound. 1.5mg per red wine bottle. Nadplus complex (80mg) = 600 bottles
Sugar and weight regulation
Protection against UVA damage (ageing)
Boost production of collagen
Oppose menopausal symptoms – prevents osteoporosis
Inhibits tyrosine kinase – involved in various degenerative diseases
Broccoli extract (sulforaphane 20mg):
Detox oestrogen pathway
Promotes cellular integrity
Repair DNA damage from reactive oxygen species (ROS) chemicals, viruses and radiation
Supports immune system plus anti-ageing
Helps eliminate dangerous metals
Assist in liver phase 2 detox
20mg in n=NAD complex = 4.5kg broccoli
Pink marine algae – carotenoid that gives flamingos and salmon rosy hue
Strongest natural anti-oxidant
Primary benefit: anti-inflammatory properties
Up to 60 times more potent than Vit E, A, Lutein or pycnegenol.
Leading International anti-ageing experts: reducing wrinkles and age spots, improve moist levels, elasticity, smoothness, radiance
Vit C: Calcium ascorbate 280mg:
Increases healing rate of wounds and burns
General skin protector
Universally well-known antioxidant and anti-inflammatory protection
Production of collagen and elastin
Reverses negative effects of UV radiation in skin and indirectly reduces pigmentation
Enhancing collagen and elastin formation in skin
Reducing stress and fatigue
Is main component of collagen – protecting its stability
NB to inhibit accelerated ageing in cartilage, ligaments, joints and skin
Strengthened by Vit C
High concentrations found in muscles, skin and connective tissues
1/3rd of collagen is composed of glycine
Without glycine: no damaged tissue repair, slack skin due to UV rays, oxidation, free radical damage and wounds would never heal.
L-Carnosine 50mg: “fountain of youth)
Natural dipeptide present in all body cells
Concentration decreases with age
Ingested – reverses signs of ageing – rejuvenating effect
Prevents skin collagen cross-linking = loss of elasticity and wrinkles
Helps entire body – not just skin – holistic approach to reverse ageing
Antioxidant metal chelating activity
Vit D3 1000IU:
Not a vitamin but a hormone
Vit D3 (calciferol) assists with fatigue and prevention of breast and colon cancer.
D3 is also responsible for the normal functioning of 223 genes in the body.
Vit B7 (Biotin 0.053mg):
Especially hair and nails – beauty guaranteed
Vit B3 (Nicotinic acid i.e. Niacin 50mg):
Increase collagen production and reduce hyperpigmentation
Niacin is precursor of NAD – oxidation reduction and ATP synthesis
Royal Jelly 25mg:
A bio peptide – juvenile hormone isolates from bees
Secreted from worker bees to feed larvae for 1st 3 days – sole food for queen bee (she lives several years compared to few months of worker bee)
Chemical composition: proteins, sugars, lipids, Vit, free amino acids etc
Stimulates cell growth and metabolism
A sulphur donor in phase 2 detox
Helps synthesize glutathione – one of body’s most important natural anti-oxidants and detoxifiers
N-acetyl cysteine is rapidly metabolized to intracellular glutathione
It removes and detoxifies heavy metals like lead, mercury, arsenic
NAC repairs oxidative damage in cells and essential in DNA synthesis
Studies – reduction in some skin cancers of 80%
Trimethyl Glycine (betane 120mg):
liver needs TMG daily, most important steps in detoxification
Magnesium Gluconate 100mg:
Mother of all minerals
Zinc important in skin – acne, anti-ageing, eczema – healthy functional tissue
With age – levels of zinc decrease – tissue lose ability to maintain itself = effects of ageing
Selenium 2% 0.05mg:
metal scavenger in liver
help against cellular aging occurring in brain
defend and repair against oxidative damage – central metabolism and DNA synthesis
reduce occurrence of skin cancer by 60%
combination of ingredients researched by Centre for Human metabolomics at North West University in SA
product research by the Biochemistry Division of the North-West University in SA
certified by MCC of SA
No yeast, wheat, gluten, soy or dairy products
No artificial preservatives, flavours or colours
No sugar, salt or starch
Suitable for vegetarians
1 box = 60 100mg veggie caps
1st 2 weeks: 1 capsule per day
Thereafter 2 capsules per day (either am and/or pm)
Can be used from age 12(one capsule a day) and from age 18> 2x capsules a day
All ingredients are organically/naturally derived from pharmaceutical grade plant extracts or synthesized with the same bio-identical structure as the ingredients appear in nature. (including capsule casing)
known symptoms: possible temporary mild hot flushes, headaches and/or nausea if dose exceeded
will feel the benefits of NAD+ after 4 – 6 weeks
ideal continued use for ultimate results
Interesting Information on Liver as well as Q&A
With my initial introduction in Rome 2012 on glycation at a medical conference introduced by the head physician of NASA, it was explained how the correct supplementation is important for a better foundation for a healthier outcome/result on skin, hair and nails and overall healthier body.
The main things why we age is and discussed at this conference was:
- Oxidative stress
- DNA damage – NAD restores DNA damage
Liver Detox is Essential!!!
“Treat your body like your Ferrari” Dr/Prof Carol Benn
How do you know you need to liver detox?
You should cleanse your liver, especially if you drink alcohol, frizzy drinks, take medication that is hard on the liver and eat junk food or non-organic food. 8hrs+ work, hormonal medication, fast foods, toxins and conscious/unconscious sugar intake.
It can take up to 3years to cleanse your liver…. Non cellular approach.
Signs that you need to cleanse your liver
Abdominal bloating. Discomfort after eating
pain or discomfort over the liver (right upper abdominal area under the rib cage)
excessive fat; pot belly or roll around the upper abdomen
trouble digesting fatty foods
had gallbladder removed
dark spots commonly referred to liver spots
overheating of the body& excessive perspiration & body odour
acne/rosacea or itchy blotchy skin
unexplained weight gain and inability to lose weight even with calorie restriction
Chronic fatigue or brain fog
Joint muscle pain
Difficulty concentrating or staying focused
Increased weight gain or cellulite
Lethargic, heavy and sweet cravings
Confusion and cognitive problems
Mood swings or depression
Sleep anaemia & snoring
A Vehicle that never goes for a service, smells terrible, becomes slower because the filter never gets replaced with a new filter. We need to cleanse our filter…our liver!
Did you know that detoxing your liver is the fastest way to rid your body of toxins? Holistic Healing has a unique procedure in doing this.
Get ready to experience glowing skin and a flatter tummy!
Did you know that Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most common causes of liver disease worldwide? NAFLD can progress to Non-Alcoholic Steatohepatitis (NASH) and cirrhosis which can lead to liver cancers and the need of organ transplant. Our liver helps detoxify our blood, produces critical proteins/hormones, and helps with digestion. 7
The primary risk factor of NAFLD and NASH is obesity. Luckily, research has shown that weightless and especially bariatric surgery can lead to significant improvements in liver health as well as reversal of these diseases. Just like all other disease it is important to treat obesity and liver disease as early as possible.
Your Liver is Your Fat Burning Organ!
Most people don’t think of the liver in terms of weight loss, but the liver is responsible for helping metabolize fat.
It produces bile, which break down fat while also working like a filter to clean toxins out of our blood, helping us feel energises. Optimizing your liver health can help you lose weight and hit your health goals much quicker.
Most people struggle with overburden livers duo to a toxic diet and lifestyle.
This means their bodies are ineffective at digestion and fat breakdown, resulting in weight gain, feeling heavy, bloated and sluggish.
Detox Symptoms during Liver Detox or a Fast
Rash; Eczema; Acne; Weakness; Nausea; Dizziness; Hot Flashes; Fatigue; Bronchitis; Asthma; Headaches; Faintness; Fever; Diarrhoea;
Muscle aches; Bad breath; Stuffed nose; Running Nose; Irregular heartbeat; Irregular menstruation
Which is the function of the liver?
The liver also detoxifies chemicals and metabolizes drugs. As it does so, the liver secretes bile that ends up back in the intestines. The liver also makes proteins important for blood clotting and other functions.
Which hormones are produced by the liver?
The liver synthesizes and secretes at least four important hormones: Insulin-like Growth Factor-1 (IGF-1) Angiotensinogen. Thrombopoietin.
Importance of liver cleanse. With the combo of NAD with phase 1& phase 2 liver detox you have a more effective cellular liver detox.
You need to treat your body like your Ferrari.
What is a Telomere?
Telomere (tel-uh-meer) for Greek telos (end) and meros (part)
Telomeres are an essential part of the human cells that affect how our cells age. Inside the nucleus of a cell, our genes are arranged along twisted, double stranded molecules of DNA called chromosomes. At the end of the chromosomes are stretches of DNA called telomeres, which protect our genetic data, make it possible for cells to divide, and hold some secrets on how we age and get cancer.
Telomeres are the caps at the end of the DNA that protect our chromosomes, lie the plastic tips at the end of the shoelaces.
Without the coating the shoelaces become frayed until they no longer do their job, just as without telomeres, DNA strands become damaged and our cells can’t do their job.
DNA makes up all our cells in our body. It is the genetic material that makes us who we are. And every organ (skin, heart, liver, colon, kidneys, etc) is made up of cells. So, telomeres are vital to our health.
Our cells replenish by copying themselves. This happens constantly throughout our lives. Telomeres get shorter each time a cell copies itself.
Some Factors of Ageing
Telomere Shortening – chromosomes lose telomeres over time.
Chronological age – risk factors increase over time.
Oxidative Stress – oxidants damage DNA, proteins and lipids.
Glycation – glucose sugar binds to and inhibits DNA proteins and lipids.
Herewith some interesting videos on NAD and liver detox
Fatigue, Parkinson’s, Anxiety, brain fog, etc on NAD
What is glycation?
The bonding of a sugar molecule to a protein or lipid molecule without enzymatic regulation.
How does glycation cause aging?
This forms advanced glycation end products (commonly shortened, appropriately, to AGEs), which cause protein fibres to become stiff and mal-formed. ... The proteins in skin most prone to glycation are the same ones that make a youthful complexion so plump and springy—collagen and elastin. Jan 31, 2012
How does glycation affect the skin?
Worse—when we're exposed to UV rays, it accelerates glycation, further aging the skin. Scientists exposed glycated skin cells to UV rays, and found that the formation of AGEs increased. ... They added that AGEs “modify skin collagen by reducing skin elasticity, and one result is wrinkle formation.” Nov 24, 2017
Why is glycation bad?
Glycation, which occurs when insulin doesn't metabolize sugars properly, destroys the collagen in blood vessels (collagen is a structural protein found all over the body, not just in the skin) and ultimately causes it to become brittle and form plaque.
Is glycation reversible?
This reaction can take from a few minutes to several hours, but it is completely reversible if the blood sugar is reduced to normal levels.
NAD & glycation
NAD repair cells